Testimonial – Dr. Tobias Meyer-Zedler

Name: Dr. Tobias Meyer-Zedler
University / Institution: Leibniz Institute of Photonic Technology
Department / Research Group: Molecular imaging
Position / Title: Research group head
Research Area / Specialization: multimodal nonlinear and coherent Raman microscopy and endoscopy

1. Please briefly describe your research focus and current projects.

My current research focuses on multimodal nonlinear microscopy and endoscopy, with applications in the detection of diseases such as cancer and infections, as well as in drug delivery monitoring and characterization.
A major part of my work is dedicated to the development and translation of advanced photonic imaging technologies for biomedical and clinical applications.
An important collaborative project is the Leibniz Center for Photonics in Infection Research (LPI), which aims to advance photonic solutions for rapid diagnostics and infection research.

2. What research needs or challenge were you aiming to address when looking for a
solution ?

We aimed to address the need for sensitive, label-free, and minimally invasive imaging techniques that enable early detection of diseases such as cancer and infections.
A major challenge was the translation of advanced multimodal nonlinear imaging methods from the laboratory into clinically relevant applications, including endoscopic systems for real-time diagnostics and monitoring of drug delivery processes.

3. What factors influenced your decision to select our system ?

We selected your products because they are, to our knowledge, the only commercially available double-clad hollow-core fibers that enable broadband laser delivery while preserving peak intensity and minimizing additional dispersion.
These properties are highly important for coherent Raman endoscopy, where efficient ultrashort pulse delivery and signal integrity are critical. In addition, the capability to collect the generated signal through the same fiber provides a highly attractive and practical solution for compact endoscopic implementations.

4. How has your experience been using our system in your research work ?

Our experience with the products has been very positive overall, particularly regarding broadband ultrafast pulse delivery and the integration of excitation and signal collection within the same fiber architecture. These features are highly valuable for coherent Raman endoscopy applications.
One remaining challenge is that the optical losses are still higher than desired for some applications, especially where maximum transmission efficiency and signal sensitivity are critical. Nevertheless, the fiber design offers significant advantages compared to currently available alternatives.

5. Have our system contributed to any improvements in your workflow, experiments,
efficiency, or research outcomes ?

Yes, the products have contributed to improvements in both experimental implementation and system integration. The fiber design simplifies the delivery of ultrafast broadband laser pulses and enables signal collection through the same optical path, which is highly beneficial for coherent Raman endoscopy setups. The part has been accelerating our translational research activities.

6. Are there any specific features or aspects you particularly value ?

We particularly value the combination of broadband ultrafast pulse delivery with low nonlinear distortion, as well as the double-clad hollow-core fiber design that enables simultaneous excitation and signal collection. The fiber facilitates translation of coherent Raman imaging techniques toward practical biomedical and clinical applications.

7. Would you recommend our system to other researchers or institutions ? Why ?

The products can be of considerable interest to researchers and institutions working in the fields of nonlinear microscopy, coherent Raman imaging, and biomedical endoscopy.
The products provide unique capabilities for broadband ultrafast laser delivery and combined signal collection, which are highly relevant for advanced photonic imaging applications. In particular, the availability of specialized fiber designs and integrated endoscopic solutions makes them attractive for both fundamental research and translational biomedical developments.