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The BondXplorer™ SRS microscope is a nonlinear microscope allowing simultaneous imaging using various modalities, including SRS imaging of CH2 and CH3 bonds, CARS imaging, 2P fluorescence and SHG imaging. To view detailed specifications on our store, visit the product page BondXplorer multiphoton microscope.
Multimodal nonlinear microscope
The Raman and multiphoton microscopy system offered by LCT is an inverted microscope that allows for simultaneous imaging of Stimulated Raman Scattering (SRS), Coherent Anti-Stokes Raman Scattering (CARS), Second Harmonic Generation (SHG), and two-photon fluorescence (or autofluorescence). This microscope is marketed under the brand name BondXplorer™.
The detection of CARS, SHG, and two-photon signals occurs in back detection. SRS imaging is in forward detection.
Histological imaging
Powered by the state-of-the-art APE picoEmerald FT laser, the BondXplorer delivers fast, shot-noise-limited coherent Raman imaging accross a wide spectral range of 300 cm⁻¹ to 4000 cm⁻¹. With rapid sub-1.5 second tuning capabilities, the platform seamlessly enables high-throughput, fast hyperspectral imaging.
Control software
The SRS microscope is controlled by a dedicated software that allows control of various functionalities (field of view, integration time per pixel, objective movement in z, motorized stage movement in (x,y)…). In addition, the software allows control of the synchronous detection unit (necessary in SRS mode) as well as the laser system.
The software offers the user a real-time ‘Stimulated Raman histology’ image that allows for the appreciation of tissue morphology in a colorimetric code (proprietary routine developed by Lightcore Technologies) of interest to histopathologists.
For more technical information, you can download our brochure.